1992 Volume 34 Issue 3 Pages 599-607
We reported an interesting case of Crohn's disease with acute development of marked colonic stenosis. A 21-year-old man was admitted to our hospital on 11th of August 1989, with com-plaints of bloody diarrhea, abdominal pain and fever after travelling abroad. Colonoscopic examination showed multiple irregular ulcers with mucosal inflammation in the sigmoid colon, descending colon, transverse colon segmentally, and circumf erential ulcers seen in the ascending colon and cecum. Symptoms and inflammatory reactions were improved gradually but bloody diarrhea continued under medical treatment with intravenous hyper-alimentation and antibiotics. Four weeks later, barium enema study revealed longitudinal ulcers and cobblestone appearance with marked tubualr narrowings in the colon. Total colectomy was done on 27th of September 1989, because of abdominal pain due to stenosis and continuous bloody stool. Hitological findings of the resected specimen disclosed that multiple longitudinal and irregular ulcers (ul-II) were seen. Dilatation of small vessels with congestion in the mucosal layar, marked submucosal fibrosis and sarcoid-like granulomas were observed. Crohn's disease was confirmed with those findings.