1992 Volume 34 Issue 4 Pages 846-854_1
A 70-year-old man took an endoscopic examination in our hospital because of epigas-tric discomfort. A small elevated lesion divided by grooving erosions was found in the lesser curvature of the gastric antrum. In the biopsy specimen taken from this erosion, diffuse infiltration of B-lymphocytes with slight atypia (L26 + and MT1-) was observed. Under the diagnosis of malignant lymphoma, distal partial gastrectomy was performed on May 21, 1990. Lymphoma cells invaded to mucosal and upper submucosal layers within the extent of 0.7 × 0.5 cm in size without regional lymphonode metastasis. Pathological diagnosis of the lesion was as follows. It showed diffuse lymphoma, medium sized cell, type, B-cells (L26+, TM1- and UCHL1-). Based on reported cases, characteristic findings of early gastric lymphoma revealed by endoscopy were discussed. The findings of gastric mucosa caused by lymphoma cell infiltration seemed to be "coarse granules surrounded by grooving erosions" (cobble stone appearance), which was also the case with our minute superficial lymphoma. Dye spreading method will usefull to get these findings and contribute to the endoscopic diagnosis of malignant lymphoma of the stomach in the early stage.
