A STUDY OF AETHOXYSKLEROL-ETHANOL INJECTION THERAPY FOR BLEEDING FROM ACUTE GASTRIC ULCERS

-THE HEMOSTATIC EFFECT AND HEALING PROCESS OF ULCERS-

Abstract

We conducted a comparison study concerning the effect of hemostasis of acute bleeding gastric ulcers between the injection therapy with only ethanol and ethanol with Aethoxysklerol (AS-E) using endoscopic thechnique. Before injection with ethanol, Aethoxysklerol was injected to 3 to 4 sites around an exposed vessel in one treatment group with 28 cases. Successful endoscopic hemostasis were achieved in all patients treated with AS-E. In another group treated with only ethanol injection, we had several f ailured cases in hemostasis of gastric bleeding. At the view point of healing process of the ulcers, there were no significant difference between two treatment groups. The volume of ethanol administered was almost same in two groups. These results suggested that endoscopic AS-E injection therapy is safe and clinically effective in the treatment of hemostasis of acute bleeding gastric ulcers.