Abstract
We reviewed 37 cases (0.48%) of postendoscopic acute gastric mucosal lesion (PE-AGML) among 7, 574 cases of panendoscopy for the upper GI tract. The interval of the onset of PE-AGML was 7.3±1.5 days after endoscopy. The predirection site of the lesion was the antrum of the stomach (92%). There were no significant corelations between the PE-AGML and the following factors: age of the patient, endoscopic experiences for the patients, the month of examination, career and technique of the endoscopist. Furthermore, prophylactic therapy of diazepam injection and/or H2-blocker for PE-AGML did not show a significant difference opposed controls. On the other hand, incidence of PE-AGML was significantly higher in cases undergoing endoscopy later as a result of frequent use of the same endoscopy in a day. This study suggests that strict sterilization of the endoscopy would be more effective for PE-AGML than prophylactic therapy of diazepam injection and/or H2-blocker.