Abstract
A 62-year-old man was admitted to our hospital with complaints of dysphagia and 8 kg weight loss for the past four months. X-ray examination of the esophagus showed a giant nodular elevated lesion located in the lower two third of the esophagus. Endoscopic examination of the esophagus disclosed a reddish tumor covered with food residues and necrotized substances. As this tumor was suspected of carcinosarcoma of the esophagus by endoscopic biopsy, sub total esophagectomy was carried out. Histological and immunohitochemical studies of the surgical specimen revealed so-called carcinosarcoma of the esophagus. The tumor was measured 21.7×7.0 cm in size, which was the biggest one reported in Japan. The patient expired two months after the operation, because of multiple metastasis to the lung.