Abstract
The images obtained by electronic endoscope can be expressed by numerical values. We attempted to differentiate the stages of ulcerative colitis numerically by computer analysis of the images obtained by a magnifying electronic colonoscope, type CF-200HM. The subjects were 95 cases with ulcerative colitis and 18 normal subjects. After spraying of methylene blue on the mucosa, magnifying colonoscopy was performed. Red component was extracted from the images, scale transformation was exerted, and then binalization images were made. The ratio of non-staining area (area of gland orifice) in concerned area was calculated. As a result, the values correlated with the staging determined by symptoms, endoscopy and histology. Our approach was considered to be useful for quantitative assessment of the stages of ulcerative colitis.