THE EFFECT OF ARGON LASER ON THE MITOCHONDRIAL RESPIRATION OF ISOLATED GASTRIC MUCOSA

Abstract

We investigated the respiratory function of mitochondria isolated from gastric fundic mucosa of rabbit under irradiation of low intensity 514.5 nm light. Visible argon laser with the power of 200 mW was irradiated to the mitochondrial susupension of 2ml in volume. Restipatory function was measured by Clark-type electrode and temperature was also measured. We found that the mitochondrial respiratory function was enhanced by argon laser irradiation even taking account of its temperature elevation effect. Mitochondoria contains a lot of chromophore, such as cytochorom C which is sensitive for green light. Therefore, it is thought that green light irradiation affects certain enzyme of mitochondria. Our results may suggest the possible kintics for cell-photo-stimulation by low-intensity light irradiation.