Abstract
This case report describes a primary diffuse malignant lymphoma located at the submucosa of the entire large intestine. The patient was a 78-year-old female who hospitalized with hypoproteinemia and dyspnea. Examination of the gastro-intestinal tract was performed because of severe anemia and a bloody stool. Colonoscopy revealed diffuse verrucif orm -like erosions on the entire large intestine accompanied by a prominent ileo-cecal valve and an erosive polypoid lesion of the ascending colon. Biopsy specimens showed marked lymphoid proliferation of the submucosa of the large intestine, which revealed a malignant lymphoma of the diffuse, small cell type. Generally, primary intestinal lymphoma shows various endoscopic findings. The endoscopic findings of this case should be kept in mind in order to differentiate cases like it from inflammatory bowel diseases and infectious colitises.