Abstract
The case is a 61-year-old woman who was hospitalized for disturbance of consciousness. Renal abscess secondary to pyelonephritis were treated with CMZ for 5 days, CEZ for 26 days, LMOX for 10 days and AZT for 14 days. These treatment led to diarrhea (ten times a day) and pyrexia (37.7°C). Colonoscopy revealed yellow-white, hemispherically protuberated multiple pseudomembranes ranging from rectum to sigmoid colon, and stool culture was positive (+++) for Staphylococcus aureus and negative for C. difficile DI toxin. Administration of VCM led to disappearance of diarrhea. However, 4 months later, diarrhea reappeared 7 days following administration of PIPC because of urinary-tract infection. Colonoscopy revealed recurrence of small pseudomembranes all over large intestine. Stool was negative for C. difficile DI toxin, and stool culture was positive (+++) for Staphylococcus aureus and methicillin-resistant, indicating MRSA. This is the 6th reported case in Japan, in which MRSA was detected in pseudomembranous colitis.
