Abstract
A 34-lyear-old female visited our hospital with complaint of melena, and was diagnosed to have a submucasal tumor in the terminal ileum by X-ray and endoscopic studies. Ileocecallectomy was performed. The tumor was 10 x 9 x 8mm in diameter and consisted of white solid tissue. Microscopically, the tumor had no capsule and consisted of fusiform cells. The tumor cells revealed positive immunoreactivity to s-100 protein and NSE, on the other hand, negative to desmin and myoglobin. They also revealed positive to Alcian blue and had no seatlike structure of nuclei, so were diagnosed as neurof ibroma. Nourogenic tumor of the small intestine is very rare, especially without complication of von-Rechlinghausen disease. Thus, it is very difficult to make the diagnosis of neurof i-broma before operation like this case.