1994 Volume 36 Issue 4 Pages 750-755_1
Extramedullary plasmacytoma of the stomach is an extremely rare disease, and only about 50 cases have been reported in Japan. This is a report of a case of gastric plasmacytoma limited to the mucosal layer which was difficult to distinguish from RLH and malignant lymphoma. A 61-year-old woman visited our hospital with complaint of occasional epigastric pain. Endoscopic examination revealed the discoloured mucosal lesion on the lesser curvature from the lower body to the angle, the boundary of which was unclear, and it was accompanied by multiple redness and erosions. Because the biopsied specimen disclosed the finding of plasmacytoma, we performed total gastrectomy. In resected specimen, atypical plasma cells were widely seen from the body to antrum. Immunohistochemically these cells were monoclonally stained with IgM and x-light chain, but they were confined to the mucosal layer. This gastric plasmacytoma limited to the mucosal layer was the fourth report in Japan. According to reports of the advanced cases, the prognosis was not good at all. So the early diagnosis is desired.
