A CASE OF GASTRIC HYPERPLASTIC POLYP SHOWING RAPID GROWTH AT THE SITE OF STRIP BIOPSY

Abstract

A 60-year-old man was pointed out to have an early gastric carcinoma of ha + IIc in the prepyloric region by endoscopic examination. The histological findings at the lesion removed by strip biopsy were moderately differentiated adenocarcinoma, in which the depth of the cancerous invasion remained within the mucosal layer of the stomach. The edge was free of carcinoma. After 5 months, at the same site of strip biopsy, a new elevated lesion of Yamada's classification type III with diameter of 2cm was recognized. He had taken an H₂ receptor antagonist for 5 months after strip biopsy. The biopsy specimen of the polyp showed no malignancy. However, polypectomy was performed to do complete examination for the excised specimen. The histological findings were compatible with hyperplastic polyp with no malignancy. The mechanism of growth of the polyp was considered that the epithelium regenerated excessively at the site of mucosal defect after strip biopsy. This was a very interesting case to concern the mechanism of development of hyperplastic polyp.