1994 Volume 36 Issue 6 Pages 1175-1185
The usefulness of endoscopic naso-biliary drainage (ENBD) after endoscopic sphincter-otomy (EST) and endoscopic lithotripsy (EL) was assessed by comparing the outcome in patients undergoing ENBD with those not undergoing this procedure. Meterials and methods : EST was performed in 170 patients with common bile duct stone (CBDS) from Octobar 1985 to July 1993. Among these patients, 84 were excluded : 44 due to hyperamylasemia (>500IU) appearing 2 hours after EST, 32 because they had previously undergone percutaneous drainage, and 8 undergoing EST a second time to treat recurrence. The subjects for this study, therefore, consisted of 86 patients. These patients were divided into two groups depending on whether ENBD was performed (NBD group, 59 patients) or not (non-NBD group, 27 patients). The groups were compared in regard to the improvement in body temperature (BT), WBC, CRP, T-Bil, AIP, and LAP, two days after EST and EL. Results : Although there were no distinct intergroup differences in BT and WBC, in the NBD group and in the non-NBD group. Significant differences between the NBD group and the non-NBD group were noted in CRP, T-Bil, AlP and LAP. In the NBD group, these variables clearly improved after EST and EL compared with before therapy (p <0.005, p < 0.001, p <0.001, p <0.001, respectively) ; no improvement was evident in the non-NBD group. Conclusion : ENBD after EST and EL was evaluated to be a useful procedure for preventing early complications from occurring after these procedures and for improving inflammation and bile congestion.