Abstract
Balloon-Qcclu.ded Retrograde Transvenous Obliteration(B-RTo)was performed infour patients with solitary gastric varices from March 1993 to November 1994, and preand post-B-RTE course of the disease was examined by ultrasonic miniture probe(UMP).Pre-B-RTO UMP revealed non-echo luminal image, but UMP showed the dotted high echoarea in varices immediately after B-RTE. After temporary appearance of the dotted highecho area, non-echo luminal images were observed while the luminal shape remainedunchanged ar the luminal size reduced slightly:Then, gastric varices disappeared in allpatients. Experimentally, 5%EO was administred in vein of white rabbits'ear, andultrasonic and histopathological changes were examined at intervals. In blood vesselsshowing a non-echo luminal images, a doted high echo image appeared in the non-echolumen immediately after 5%EO infusion, which increased one minute after. Almostsimilar ultrasonic findings remained u.p to day 3 after the injection. Histopathologicalexamination revealed that endothelical cells of the veins disappeared immediately after 5%EO infusion, and that clots were noted as if to fill up the vessels. Histopathological findingsat minutes 15 after release of avascularization included edema around the extravasculer wall. At hour 1, fibrin precipitated and fibroblasts appeared in the vascular wall. At hour3, the fibrin precipitation and slightly increased fibroblasts in the vessels were still present.These results of the clinical and basic studies suggested that the dotted high echo appearingafter administration of 5%EO reflected the changes resulting from endothelialdisordersand associated occurrence of intravascular clots. It remained unknown what kinds ofhistopatholagical changes yieled the UMP finding that the nan-echo luminal imagesappeared following the dotted high echoin the gastric varices.
