Abstract
A 69-year-old female had undergone partial gastrectomy. The resected specimen showed a protruding lesion(20mm×20mm in size)with an irregular reddish rnucosa associated with a superficially depressed lesion on the oral side. Histologically, moderately differentiated adenocarcinoma(tub 2)were observed in the gastric mucosa and in a nodular leson of the submucosa. Accumnulated xanthoma cells were found around the tub 2 tissue of the submucosa, and xanthogranulama around the nodule of the subrnucnsa. Intramural metastasis took place via veins or lymphatic vessels, forming a submucosal tumor like lesion associated with accumulated xanthoma cells and xanthogranuloma. This case was thought to be rare. The patterns of growth and invasion in this case were interesting.