Abstract
A29 year old man was admitted to the Niigata Cancer Center Hospital on March, 1991with complaint of tarry stool. Endoscopic examination revealed edematous enlarged major duodenal papilla withhemorrhage. Abdominal CT scanning and celiac angiography showed tumor at the head ofthe pancreas with multiple liver m6tastasis. Histological exarnination of the specimenstaken on laparotomy for by-pass operation revealed islet cell tumor. Atotal 29.0 grs of streptozocin (1.0grs/w) had been administered. After treatment of streptozocin, the size of parlcreatic turnor was reduced and metastatic liver tumors wereundetectable on CT scanning. Therefore, it is concluded that streptozocin should be triedfor the frantment of islet cell tumor.
