Abstract
We report a patient with giant Yamada (Y)-3 type gastric hyperplastic polyp developing after endoscopic mucosectomy for early gastric cancer. Sixty two year old man wasadmitted to our hospital due to endoscopic mucosectomy for early gastric cancer (typeIlc+Ila) in the antrum. The removed lesion revealed histologically as well differentiatedtubullar adenocarcinoma confined to the mucosa. Follow-up endoscopy about 10 monthsafter mucosectomy showed a polypoid lesion in the resected site, which was identifiedhistologically hyperplastic polyp. The polyp had grown up to Y-3 type, sized about 25mmin diameter, so it was resected by endoscopic polypectomy. A case of gastric hyperplasticpolyp developing after endoscopic mucosectomy for early gastric cancer has been rarelyreported in Japan. The mechanism was still unknown, but was thought that excessiveregeneration of epithelium was promoted by formation of ulcer after endoscopicmucosectomy, administration of H2-receptor antagonist and mechanical stimulation byincreased peristalsis.
