Abstract
An attempt was made to elucidate endoscopic and histologic characteristics of benignprotruding lesions which arise at the scar of endoscopic mucosal resection(EMR)for earlygastric carcinoma(EGCa)and gastric adenoma. These benign protruding lesions developedin 70f 23(30%)lesions of EGCa and in 4 of 27(15%)lesions of gastric adenoma which hadbeen followed at least one year after EMR. The shapes of benign protruding lesions wereas follows; 6 Yamada(Y)1-2 type elevations, 4 flat elevations, and one Y-4 type polyp.The incidence of developing henign protruding lesion after EMR was 44%in the antrumand higher than the incidence of 12%in the body of the stomach. Histologic examinationof benign protruding lesions after EMR revealed hyperplasia in 6, intestinal metaplasia in 3, pyloric glands ln l and and surface epithelium with granulation tissue in 1 lesion, respectively. It may be possible that the potential of hyperplasia which may reside in apparentlynormal mucosa sorrounding EGCa or gastric adenoma might wake up during the healingprocess of the EMR ulcer and develop to benign protruding lesions.
