A CASE OF ULCERATIVE COLITIS ASSOCIATED WITH DISSEMINATED INTRAVASCULAR COAGULATION AND TOXIC MEGACOLON

Abstract

A 51-year-old female presenting bloody diarrhea was treated with steroid, 60-80 mg/ day, i. v., but her symptons did not improve. She also developed disseminated intravascular coagulation (DIC), and recovered from DIC with medical treatment. Then she developed toxic megacolon and operation was performed. No cases complicated with both DIC and toxic megacolon, and cured by operation like this case, have been reported in Japan. The resected specimen showed peculiar longitudinal residual mucosa like islands. DIC may have occurred by inflow of endotoxin into blood.