Abstract
Gastric adenoma was found 213 lesions in 190 cases among 14, 000 endoscopic studies during the period between Oct. 1978 and Apr. 1995. We studied the cases of gastric carcinoma with gastric adenoma which were classified into four groups based on same or different area and same time or follow-up periods. The frequency of gastric adenoma was 1.3% (mean age: 62.4). Male to female ratio was 1.9:1 in overall. The frequency of gastric carcinoma with gastric adenoma was 19.0% (36/190 cases). The cases of gastric carcinoma in adenoma were 14 cases (6.6%). These adenomas showed a reddish, large and/or depressed component. The cases of gastric carcinoma with adenoma in different area were 16 cases (7.5%). In all cases, gastric carcinoma were located at the same area or oral side of gastric adenomas. The cases of gastric carcinoma in adenoma found during the follow-up period were 5 cases and the case of gastric carcinoma with adenoma at different area found during the follow-up period was only one case. These observations indicated evidently that gastric mucosa with adenoma has the malignant potential as compared to normal mucosa without adenoma, suggesting that it may be possible to pick up high risk patients for malignancy based on endoscopic findings. When a patient has gastric adenoma, it is necessary to bear in mind that gastric carcinoma may develope in the same or different areas and at same time or during the follow-up period. Careful endoscopic observation of the same and oral side area of gastric adenoma is needed.
