Abstract
During the period from 1985 Dec.1896, 11234 colorectal neoplastic lesions wereexamined. Lesions were histopathologically classified into two types:adenoma(n=10215)and early cancer(n=1019). Of the early cancers, 771 were confined to the mucosa and 248had invaded the submucosa. Endo5coplC findings were evaluated by the multivariatestatistical analysis. We classified the submucosal extension of early cancer according tothe vertical and horizontal level of invasion. We also classified pit pattern into 6 types. Inthe examination of submucosal invading cancer, vessel invasion occurred in smlb extensioncancer and lymphonodus metastasis occurred in smlc and rnore advanced stages extensioncancer. Therefore endoscopic mucosal resection is su.itable in smla and smlb extensionwithout vessel invasion. Based on this result, we evaluated endoscopic findings thatinfluence to the depth diagnosis of early colorectal cancer by the multivariate statisticalanalysis. The factors that are associated strongly with the depth diagnosis are as fellows1.grass configuration, tumor size, type V pit pattern, sclerous change, sharply demarcateddepressed surface, prominence from the surface of depression in the case of depressed typeearly cancer, 2. tumor size, type V pit pattern, expanded change, sclerous change in the caseof protruded type, 3. grass configuration, tumor size, type V pit pattern, sclerous change, radiating fold in the case of LST. The accuracy of the depth diagnosis from endoscopicfindings by the multivariate statistical analysis in any forms early cancer were more than 90%.