INFLUENCE OF HRLIC4BACTRR PYLORI INFECTION ON THE U:LCER H:EA:LING AND THE GASTRIC MUCOSAL BLOOD FLOW OF THE EMR-INDUCED ULICER

Abstract

We studied the differences in the ulcer healing and the gastric mucosal blood flow of the EMR-induced ulcer, between 34 Helicobacter pylori(HP)positive cases(41 lesions)and 13negative cases(171esions). There were no significant differences in the ulcer healing and the changes in mucosal blood flow of the ulcer margin during the time course(1 day, 1 week, 2weeks, 1month, 2months and 3 months after EMR)studies. However, at the endoscopically healing stages, rnucosal blood flow ratio(mucosal blood flow of the ulcer margin/that of the surrounding mucosa)of the SIP negative lesions was significantly higher than that of the HP positive lesions. fur results suggest that HP infection affects local factors and reduces mucosal blood flow of the ulcer margin at the healing stages.