ENDOSCOPIC DIAGNOSIS AND MANAGEMENT OF COLORECTAL NODULE-AGGREGATING LESIONS

Abstract

To determine the management of eolorectai nodule-aggregating lesien, we studied the relationship between endoscopic findi:ngs arld histopathological results (mainly, incidence of carcinoma and depth of invasion) in 45 lesions (44 cases)treated by endoscopic or surgical resection. Resected specimens revealed 22 adenomas and 23 carcinomas (carcinoma in adenoma; 20 lesions), which included 17 intramucosal carcinomas and 6 invasive carcinomas (sm; 5 lesions, mp; 1 lesion). The frequency of accompanying carcinoma increased significantiy in iarger lesions of the tumor size and iesions with giant noduie or depression on the tumor. And the difference in the frequency of invasive carcinoma between lesions with depression and those without depression was statistically significant. In addition, it is essential to perform endoscopic ultrasonography for the dzagnosis of depth of invasion. From the point of view of tumor size, endoscopic resection was safe and certain in lesions with the diameter smaller than 40mm. clinical management of colorectal nodule-aggregating lesions should be determined syntheticically in accordance with abovementioned results.