Abstract
During a period of more than 10 years before December 1991, 169 gastric ulcer patientshad been followed up over one year. The 160 ulcer patients included 126 males and 34 femaies. Eleven gastric cancers were detected among the 160 gastric ulcer patients. These gastric cancer lesions were located in different sites of the stomach from gastric ulcers. These cancer cases were detected in g males and 2 female patients with gastric ulcer. Of the 11 gastric cancer patients, 10 with early gastric cancer had 13 IIc type lesions. One patient had a Sorrmann 4 type lesion. We calculated the relative risk of developing gastric cancers in other locations than the original ulcers among study subjects as compared with the risk in the general population. Nine cases of gastric cancer were observed in 126 male subjects and 1.45 cases were expected from an age-specific incidence rate obtained from MIYAGI Cancer Registry. The ratio of observed/expected number of new cases (95 confidence interval) was thus 6.19(2.2-11.76), suggesting an increased risk of developing gastric cancers in patients with gastric ulcer.
