Abstract
A 63-year-old man was admitted to the hospital in May 199 because of waterydiarrhea and lower abdominal pain. On physical examination, several cervical lymph nodes were palpable but hepatos-plenomegaly was not observed. Peripheral blood picture was normal. The serum totalprotein value was moderately decreased and immunoglobulin M was slightly elevated.Examination of the gastrointestinal tract with X-ray and endoscopy revealed multiplepolypoid lesions in the small and large intestine and hypertrophy of mucosal folds on theupper body of the stomach. Histological examination of biopsied specimen from the stomach, duodenum, terminalileum, large intestine and cervical lymphnode disclosed non-Hodgkin's, diffuse, mediumsized, B-cell type malignant lymphoma. And centrocyte-like cells which resembled thecentrocytes of the follicular centers proliferated diffusely but did not infiltrate the epith-elial glands. After chemotherapy with VEPA, X-ray and endoscopic findings of the gastrointestinaltrust improved markedly, and diarrhea and abdominal pain also disappeared. We reported a case of malignant lymphoma of the gastrointestinal truct of which X-ray and endoscopic appearances were polypid lesions in the intestine and hypertrophy ofmucosal folds in the stomach.
