CHEMOTHERAPEUTIC EFFECTS ON GASTRIC ENDOCRINE CELL CARCINOMA WITH MULTIPLE LIVER METASTASIS: REPORT OF TWO CASES

Ryozo IWAZAKI; Akihito NAGAHARA; Kazuki OHTA; Katsuyori IIJIMA; Yasuhiko OHNO; 前広 康平; Ryuichi OHKURA; Hiroto MIWA; Nobuhiro SATO; Yoshinori HOSOKAWA; Toshiharu MATSUMOTO; Ryo WADA

doi:10.11280/gee1973b.40.1889

Ryozo IWAZAKI, Akihito NAGAHARA, Kazuki OHTA, Katsuyori IIJIMA, Yasuhiko OHNO, [in Japanese], Ryuichi OHKURA, Hiroto MIWA, Nobuhiro SATO, Yoshinori HOSOKAWA, Toshiharu MATSUMOTO, Ryo WADA

Author information

Ryozo IWAZAKI
Department of Gastroenterology, Juntendo University of medicine
Akihito NAGAHARA
The first. Debpartment of pathology, Juntendo University of medicine
Kazuki OHTA
The first. Debpartment of pathology, Juntendo University of medicine
Katsuyori IIJIMA
The first. Debpartment of pathology, Juntendo University of medicine
Yasuhiko OHNO
The first. Debpartment of pathology, Juntendo University of medicine
[in Japanese]
The first. Debpartment of pathology, Juntendo University of medicine
Ryuichi OHKURA
The first. Debpartment of pathology, Juntendo University of medicine
Hiroto MIWA
The first. Debpartment of pathology, Juntendo University of medicine
Nobuhiro SATO
The first. Debpartment of pathology, Juntendo University of medicine
Yoshinori HOSOKAWA
The first. Debpartment of pathology, Juntendo University of medicine
Toshiharu MATSUMOTO
Laboratory Division, Kanto Rosai Hospital
Ryo WADA
Laboratory Division, Kanto Rosai Hospital

JOURNAL FREE ACCESS

1998 Volume 40 Issue 10 Pages 1889-1896

DOI https://doi.org/10.11280/gee1973b.40.1889

Details

Abstract

We treated two cases of gastric endocrine cell carcinoma with multiple liver metas-tasis by CAP⋅ PVP Hybrid chemotherapy. Case 1 was a 58-year-old man. The cancerwas type 3'shaped and accompanied with enormous liver metastasis, and chemotherapywas not effective to the tumors. Case 2 was 69-year-old-man, with type 5'gastric cancerwith multiple liver metastasis. In this case, type 5'gastric cancer with liver metastasis wasremarkably reduced by two courses of chemotherapy. However, re-chemotherapy was noteffective after liver metastasis had rapidly enlarged. Gastric endocrine cell carcinoma isarare disease with a poor prognosis and early metastasis to the liver. Effective therapeuticstrategy, including chemotherapy, needs to be urgently established.

Corresponding author

Register with J-STAGE for free!