Abstract
The case is a 63-year-old man(at the first examination)who had been suffering fromrheumatoid arthritis from age 28. In 1981, he was hospitalized for melena, but detailedexamination revealed no bleeding source. Thereafter, he repeated hospitalization formelena and in 1985(age 67), colonoscopy revealed multiple irregular ulcers in the terminalileum. Analgesic anti-inflammatory suppository, Diclofenac, which was administratedsince three years ago, was discontinued, and the ulcers were disappeared. In 1991 (age 73), pyrexia and watery diarrhea occurred and colonoscopy revealed small psoudomembranesin the rectum and mutiple maculosus aphthoid lesions having red halo at their circumferances in the sigmoid colon. Gold preparation(aurothiomalate), which was given for the past5years(total 3730mg), was discontinued and subsequently the symptoms disappeared. This patient's colorectal mucous membrane recovered to the normal after administratingVancomycin for two weeks.
