PEPTIC ULCERS CONSIDERED FROM THE ENDOSCOPIC VIEWPOINTS

Abstract

The author discussed several points which were focussed during routine endoscopic exami-nation of many peptic ulcers, and also reported results of our pathophysiological studies associated with these problems. The contents of this paper were as follows: 1. duodenal ulcer scars (S'2), 2. gastric ulcer scars which had not been recognized by endoscopy, 3. association of ulcer size and the healing rates, 4. maintenance therapy and recurrence of ulcers, 5. maintenance therapy and tolerance to H2RA, 6. NSAID-associated ulcers, 7. production of prostaglandin in mast cells, 8. ulcers in elderly, 9. H. pylori and ulcer recurrence, 10. H. pylori eradication and the changes of the endoscopic feafures of gastritis, 11. H, pylori and interleukin-8, 12. mecha-nism of interleukin-8 release, 13. natural history of peptic ulcers.