Abstract
The patient, a 72-year-old woman, was pointed out elevated lesion with ulceration at the upper body of the stomach and admitted to our hospital. No malignancy was shown on the endoscopical biopsy. However, operation was performed because macroscopically, the lesion was not negrected malignancy. Histological study revealed granuration with hyperhyalinization and increase of the collagen fiber in the submucosal layer. The cause of the lesion is unknown, but was considered that it might have been related to a long-term taking of the histamin-2 blocker and anti-ulcer drugs.