PARENTERAL ADMINISTIRATION OF A SOLUTION WITH ELIECTROLYES AND POLIYETHILENE GLYCOL 4000 TO A PATmNT WITH HEPATIC COMA SECONDARY TO EISOPHAGEAL VARICES RUPTURE

Abstract

A65 year-old rnan with alcoholic liver cirrhosis was admitted complainillg Qf hematemesis and melena. Emergerlt upper gastro-intestinal e:ndoscopy revealed rupture of the esophageal varices, which was treated by endoscopic vareceal ligation successfully. On the next day, serum ammonia was elevated to 458μg/dl and he fell into a corna without evacuation. To wash out the blood iil the gastro-illtestinal tract, 21iter of a solution with electrolyes and polyethilene glycol 4000(MGV-5:NIFLEC^R)was adnlinistered in 3 hours through tlle nasal tube. After several times of diarrhea, he recovered from coma gradually. Pernasal admillistration of MGV-5to a patient with hepatic coma secolldary to esophageal varices rupture is useful.