A CASE OF DIFFUSE INFILTRATING POORLY DIFFERENTIATED ADENOCARCINOMA OF THE ESOPHAGOGASTRIC JUNCTIONAL REGION PROBABLY ARISING IN BARRETT'S ESOPHAGUS

Abstract

A 73-year-old man was admitted to our hospital with back pain. An upper gastrointestinal series showed Barrett's esophagus, sliding hernia, and a diffuse infiltrating cancer with defect of esophagogastric junction, measuring 2.5 cm in diameter. Biopsied specimen revealed signetring cell carcinoma. Lower esophageal resection and cardiac gastrectomy was performed. Histological examination of the resected specimen revealed poorly differentiated adenocarcinoma of the esophagogastric junctional region probably arising in Barrett's esophagus (pType 4ns, pT2(mp), por+sig, infβ, ly2⋅v0, pN1, EG, 10.5×6.5 cm). We reviewed cases of poorly differentiated adenocarcinoma of the esophagogastric junctional region and Barrett's esophagus.