2001 Volume 43 Issue 9 Pages 1878-1884
We developed the simple and safe method of the endoscopic transpapillary biopsy for pancreato-biliary diseases by using the ERCP catheter-guided technique. A fine biopsy forceps with 1 mm in diameter was inserted to the bile duct or main pancreatic duct through the ERCP catheter to approach the focal lesion and biopsy was carried out repeatedly under viewing the image of fluoroscopy. The diagnostic sensitivity for pancreato-biliary carcinoma was 64.3 (18/28). There was no significant difference of positive rate of diagnosis among the location of the lesions. To biopsy specimens from the center of the obstructive lesion as well as to take at least five specimens from a lesion may improve the accuracy of the diagnosis. This technique allows us to perform the biopsy of the lesions located in the pancreato-biliary tract safely and repeatedly and was considered useful for the histologic diagnosis of pancreato-biliary diseases.