Abstract
We encountered two patients with ulcerative colitis who had ulcerations and inflammation in the terminal ileum and/or at the ileocecal valve. In both patients, because the ileocecal lesions were en.doscopically atypical of ulcerative colitis, superimposition of infectiou.s ileocolitis was suggested. Followlng irnmediate antibiotic treatments, their symptoms were rapidly relieved, and their colonoscopic findihgs improved. Isolation of Campylobacter jejuni and Salmonella enteritidis by a bacterial culture of the biopsy specimens, confirmed the complication of bacterial infection. Therefore, when we manage ulcerative colitis, we shQuld bear in mind the possible superimpositiQn of a bacterial infection.