Abstract
We reported a rare case of primary malignant lymphoma of the esophagus without extraesophageal involvement. A 69-year-old woman was admitted to our hospital because of dysphagia. An upper gastrointestinal series showed several longitudinal giant folds from the upper to the lower portion of the esophagus. Endoscopic view of the esophagus showed the giant mucosal folds with smooth mucosal surface. EUS showed a hypoechogenic thickening of the third layer along the whole length of the esophagus. The internal echo pattern is slightly irregular. Endoscopic mucosal resection (EMR) was performed. Biopsy specimen taken from the ulcer after EMR showed a diffuse medium-sized B-cell lymphoma. Chemotherapy was performed with modified CHOP (cyclophosphamide, vindesine, pirarubicin, prednisolone). A follow-up barium study and endoscopy showed regression of the esophageal mass after chemotherapy.
