2004 Volume 46 Issue 7 Pages 1364-1367
A 46-year-old woman developed abdominal pain, diarrhea and tarry stools while she was treated with anti-tuberculosis agents for pulmonary tuberculosis. Except for the anti-tuberculosis agents, she did not take any antibiotics before admission. Endoscopic examination of the colon revealed many pseudomembranous lesions in the lower large intestine. Bacterial culture of the coat was negative for Clostridium difficile and any other pathogenic organisms. However, Clostridium difficile toxin was positive. The pseudomembranous colitis was successfully controlled by discontinuation of the anti-tuberculosis drugs along with the administration of vancomycin and lactic acid bacteria. We reported this case because the delayed onset of pseudomembranous colitis after antituberculous chemotherapy is rare.
