Abstract
Two rare cases of T cell type primary esophageal malignant lymphoma were reported. Only six cases of T cell type esophageal lymphoma has been reported in Japan, while at least twelve cases of B cell type has been reported. One was a 76-year-old man with dysphagia. Barium swallow and endoscopy showed a large ulcer on a tumor at the upper esophagus. Biopsy revealed diffuse large lymhocytes infiltration and immunohistological examination disclosed UCHLI (+) but LC26 (-). The patient had HTLV-I antibody, and proviral DNA for ATLL was shown by the Southern blotting. From these findings, the primary esophageal malignant lymphoma was induced by ATLL. The second case was a 78-year-old female who visited our hospital due to dysphagia. Barium swallow and endoscopy showed multiple ulcerous lesion on the tops of large folds of the upper esophagus, mid-esophagus lesion apparently covered by normal mucosa and lesion with multiple erosion on low elevated submucosal tumor of the lower esophagus. The lesion of mid -esophagus was negative on lugor staining and biopsy specimen taken at that regions disclosed diffuse infiltration of medium-sized lymphocytes infiltration. The flat type of the lesion has not been reported so far. Immunohistological examination of the cells disclosed UCHLI (+) but LC26 (-).
