Abstract
A 26 year-old man was diagnosed as duodenal ulcer with a complait of epigastralgia. Six months later, he had tarry stool and was found on gastroscopy to have longitudinal ulcers in the duodenum. Diagnosis was made as Crohn's disease localized at duodenum without other lesion. We gave him prednisolone, mesalazine powder, proton pump inhibitor, and enteral nutrition. After the treatment, remission had continued for eleven months. He admitted to our hospital due to loss of appetite and pyrexia. Gastroscopy showed redness in the antrum and narrowing of the second portion of duodenum. However, we could not pass the scope beyond the narrowing. His symptoms and inflammatory sign was improved by complete bowel rest. Crohn's disease localized in the gastroduodenum is rare. Crohn's disease should take into consideration in the diagnosis if benign ulcerative lesions of upper gastroduodenum were noted.