Abstract
A 43-year-old woman who had suffered from mucous diarrhea over a week visited Taigenkai hospital in April 2005. Colonoscopy showed an edematous mucosal appearance with indistinct vascular transparency. Histologically, biopsy specimens of the colon and rectum showed prominent subepithelial collagen-layer thickening (10 25μm) without lymphocyte infiltration into the colonic epithelium. She had complained the similar symptom about 7 years before. A case of Collagenous colitis observed such a long time has been rarely reported in Japan.
