MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) LYMPHOMA OF THE DUODENUM IMPROVED BY ERADICATION OF HELICOBACTER PYLORI : CACE REPORT AND REVIEW

Abstract

A 67-year-old female presented at our hospital with nausea . Endoscopic examination revealed a granular lesion with erosion on the anterior duodenal wall . We diagnosed this lesion as mucosa-associated lymphoid tissue (MALT) lymphoma by endoscopic biopsy . Endoscopic ultrasound (EUS) showed that the invasion was limited to the superficial submucosa (sm). Eradication of Helicobacter pylori (HP) with antibiotics induced spontaneous remission of the lesion. No evidence of recurrence has been observed for 12 months after the antibiotic treatment. In Japan, based on the findings of the case reports on primary MALT lymphoma of the duodenum, bulbar lesions should be treated with antibiotics because they may be relared to HP infection. These reports suggested that the lesions distal to the descending duodenum were related to other mechanisms.