Abstract
Background : It is difficult to make the objective estimate of V, pit pattern in colorectal tumors. In the current study, we define the shapes of irregular pits and perform the scoring of irregular pits, and analyzed the correlation between pit scores and the histological diagnosis. Methods : One hundred thirty cases (adenoma, 73 cases ; cancer with the depth at m to sm <1000μm, 35cases ; cancer with the depth sm≥1000μm, 22cases), which had been diagnosed histologically as colorectal tumors from January, 2002 to September, 2005 at Kyoto Prefectural University of Medicine and had observed pits with a magnifying endoscope, were analyzed in the current study. We classified 5 magnifying endoscopic findings of irregular pit as follows : 1. irregularity of pit shape, 2. existence of borderless small round pit, 3. heterogeneous area between pits, 4. existence of unclear pit about beginning and ending, 5. more than 2 branched pits. The scores of irregular pits were calculated with each tumor. A statistical analysis was performed which findings were mostly related to cancer. We calculated pit score with significant findings of irregular pits in each tumor and analyzed the correlation between pit scores and the depth of cancer. Results : Four irregular pit findings were significantly related to cancer . The odds ratio showed that the existence of the irregularity of pit shape was mostly related to cancer. Pit scores significantly increased more in cancers with the depth sm ≥1000, am than in cancers with the depth of m to sm < 1000μm. Conclusions : The scoring of irregular pit detected by magnifying endoscopy in colorectal tumors is a promising method to diagnose the existence of cancer and the depth of cancer.
