2008 Volume 50 Issue 3 Pages 400-405
We retrospectively evaluated transpapillary biopsy and brushing cytology for the diagnosis of pancreatic carcinoma. Those procedures were consecutively performed in the cases that ERCP showed the main pancreatic duct stenosis or obstruction. The subjects are 163 of 385 cases of pancreatic carcinomas, which underwent at least one transpapillary biopsy or brushing cytology. We performed endoscopic pancreatic biopsy (EPB) in 145 of 163 pancreatic car cinomas from April 1997 to March 2006, brushing cytology in 74 of 163. The cancer-positive rate in EPB was 32% (46/145) and in brushing cytology was 65% (48/74). Overall cancerpositive rate in any of those procedures was 48% (79/163). But brushing cytology cancerpositive rate was recently improved to 72% (33/46) after the cytotechnologist was participated in the procedure for immediate interpretation of the cytology. Pancreatitis was occurred in 9% (15/163) as a complication, which was conservatively treated and recovered in all the cases.