2018 Volume 15 Issue 4 Pages 270-275
Background: Cholangitis, one of the most common complications in patients who undergo pancreaticoduodenectomy (PD), can occasionally turn fatal. However, the risk factors for the development of cholangitis after PD remain unclear. The aim of this study was to investigate the risk factors for cholangitis at our hospital.Methods: We performed a retrospective cohort study including 190 patients who underwent PD at our institution between January 2008 and August 2015. We investigated the relationship between the occurrence of cholangitis requiring hospitalization after PD and other clinicopathological factors. Results: Cholangitis occurred in 22 patients. Using the receiver operating characteristic curve, we calculated the cut-off value as 8.2mm (AUC: 0.6629, sensitivity 0.68, specificity 0.64, Youden index). We observed that a preoperative diameter of the bile duct<8.2mm was significantly correlated with the incidence of cholangitis after PD. No statistically significant correlation was detected between cholangitis and other clinicopathological factors. Conclusion: The present study suggested the possibility that a preoperative bile duct diameter<8.2mm could be a risk factor for cholangitis after PD.