Clinical bacterial isolates from hepatobiliary infection and trend of antibiotics susceptibility

Abstract

Pathogens isolated from hepatobiliary infection during 10 years were investigated in a multicenter study in Japan. 508 strains (bacteria and fungi) were obtained from 232 cases. These strains were divided to community-acquired infection (CAI) and postoperativeinfection (POI), and also divided to former 5 years and later 5 years. Among CAI, the isolation rate of Enterococcus spp. was highest and followed by Escherichia coli, Klebsiella spp. and Enterobacter spp.. Among POI, the isolation rate of Enterococcus spp. was the highest, followed by Enterobacter spp. and Bacteroides spp.. Among POI, the rate of Enterococcus spp. in later period was higher than that of former period. About major pathogens, susceptibilities to antimicrobial agents were not getting worse.