2019 Volume 16 Issue 1 Pages 75-79
A 74-year-old man was referred to our hospital due to pancreatic head cancer with obstructive jaundice. He was diagnosed as locally advanced cancer with massive arterial involvement and jaundice was treated by placing a bili-ary stent. He was treated with chemotherapy (Gemcitabine and nab ─Pacritaxicel). Thirty ─one days after starting chemotherapy, he had high fever and, 2 days later, he was transferred to our hospital with unconsciousness. The blood examination revealed severe acidosis and hemolysis. Computed tomography revealed alveolar internal struc-ture in the posterior segment of liver. He died 2hours after transfer despite intensive case. Since Clostridium perfrin-gens (CP) was identified from the blood culture sample, the liver gas gangrene was supposed to be caused by CP in-fection. The liver gas gangrene caused by CP infection is a lethal disease with severe hemolysis. During multidisciplinary therapy for pancreatic cancer, especially for patients with biliary stent, CP infection should be con-sidered when patient has infection signs and early intervention is the key for recovery.
