2019 Volume 16 Issue 2 Pages 87-92
【Purpose】Inflammatory bowel disease (IBD) patients have an increased risk of fungal infections owing to fungal translocation and a compromised host. We investigated the incidence of perioperative ocular candidiasis in cases of IBD. 【Method】Ulcerative colitis (UC) and Crohn disease (CD) patients who underwent a laparotomy at Hyogo College of Medicine between January 2010 and November 2016 were enrolled in this study. 【Result】Of 421 UC pa-tients, 5 (1.2％)had ocular candidiasis, while that was seen in 3 (0.7％) of 401 CD patients. All patients had a Cen-tral venous catheter. Fungal testing of blood cultures detected Candida albicans in 7 cases (87％). β.D glucan level was elevated in 6 (75％). 4 (50％) had no eye symptoms. There were 3 with endophthalmitis and 5 with chorioreti-nitis expanding to macula lutea. All patients were monitored by ophthalmologists and received intravenous flucon-azole, and no patients had fluconazole intravitreously or vitreous surgery. 【Conclusion】There were many progres-sive ocular candidiasis in IBD patients. It is important to perform in IBD patients with fungemia screening by ophthalmologists.
