2023 Volume 20 Issue 2 Pages 140-154
Acute-phase response affects the general condition in critical ill patients in intensive care and critical care. It is analyzed whether a patient is in urgency and severity in intensive care unit (ICU). In the process with the damage-associated molecular patterns after surgery, we need to be careful of infectious diseases to prevent pathogen-associated molecular patterns and the augmentation of inflammation and cell death in ICU patients. Intensive care is operated through multidisciplinary collaboration among doctors, nurses, clinical engineers, pharmacists, physical therapists, occupational therapists, speech therapists, registered dietitians, and clerical staff. It needs systemic management of pathology, diagnosis, treatment and infection control in critical ill patients. This article summarizes the consideration and guides in systemic management and infectious disease control in intensive care in Japan.