2024 Volume 20 Issue 5-6 Pages 519-526
Purpose: This study was aimed to evaluate the efficacy of preoperative skin cleansing with Olanexidine Gluconate (OLG) compared to Povidone-iodine（PVI）in preventing superficial incisional surgical site infection (S-SSI) in hepato-biliary-pancreatic open surgery. Methods: We investigated patients who underwent open hepatectomy or pancreatectomy from October 2018 to March 2023 at the Department of Hepato-Biliary-Pancreatic Surgery, Ehime University. PVI was used in all cases until December 2020 (PVI-group), while OLG was used in all cases from January 2021．We surveyed the presence of S-SSI based on CDC guidelines. We also evaluated patient demographic data, anthropometric parameters, and perioperative data. Result: The PVI and OLG groups included 166 and 133 patients, respectively. The incidence of S-SSI was 3.0% (5 patients) in the PVI group and 2.3% (3 patients) in the OLG group, indicating no statistically significant difference. Conclusion：OLG did not show a significant reduction of S-SSIs. Therefore, depending on the cost and convenience, we can use both antisepses properly.
