2024 Volume 21 Issue 2-3 Pages 317-324
The study investigated the association between postoperative infectious complications and tumor recurrence in patients undergoing curative surgery for advanced esophageal cancer. The research was conducted at a single institution through a retrospective analysis. The study included 82 cases with Stage Ⅱ or Ⅲ cancer and a follow-up period of at least one year. Through univariate and multivariate analyses, risk factors for infectious complications and recurrence were identified. Serum albumin levels（Alb）showed a notable trend as a risk factor for infectious complications（Odds ratio 6.9, P＝0.07, 95％ confidence interval 0.82-66.95）, while a GPS（Glasgow Prognostic Score）of 1 or higher based on Alb levels was identified as a significant risk factor for recurrence（Hazard ratio 3.81, P＝0.04, 95％ confidence interval 1.04-24.91）. Although infectious complications occurred in patients with advanced esophageal cancer, the study did not find a significant association between these complications and tumor recurrence or metastasis. However, it is worth noting that improving nutritional status, as indicated by preoperative Alb levels, may contribute to reducing both infectious complications and the risk of recurrence. Comprehensive strategies should be considered to address these issues effectively.
