Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
Print ISSN : 0300-9173
Case Reports
A case of metronomic chemotherapy as an alternative cancer therapy for palliation
Kazumi Yamashita, Atsuko Nabeshima, Hiroko Kondo, Tetsuhiko Nagao, Yuichi Hara, Yuzi Naritomi
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2009 Volume 46 Issue 3 Pages 264-268

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Abstract
An 82-year-old woman underwent colostomy and standard chemotherapy using tegafur/uracil and calcium folinate under a diagnosis of colon cancer. Recurrence occurred, with pulmonary metastasis, hydroureter, and numbness in the low extremities. When admitted to our palliative care unit, she and her family wanted to have mild and minimally toxic chemotherapy. We initiated oral combination of UFT and cyclophosphamide metronomic chemotherapy. She was able to eat for more than 7 months. Her body weight was maintained, and tumor markers were kept suprressed until her death. This case suggests the usefulness of an oral anti-cancer drug low dose metronomic chemotherapy as an alternative cancer therapy in elderly cancer patients requiring palliation.
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© 2009 The Japan Geriatrics Society
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