Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
Print ISSN : 0300-9173
Age-Related Alterations in the Immunoregulatory System
Tomio Tada
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1986 Volume 23 Issue 2 Pages 131-133

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Abstract
Age-related alterations of the lymphocyte subsets as determined by the flow cytometry analyses and by the abilities to produce or accept interleukins were described. Experiments with the aged→young and young→aged radiation bone marrow chimeras suggested the central importance of the thymic environment rather than the stem cell itself in the age-related functions of the thymusderived lymohocytes.
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© The Japan Geriatrics Society
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